Total body water and acute kidney injury in myocardial infarction

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Acute kidney injury (AKI) in patients with myocardial infarction (MI) is associated higher morbidity and mortality a incidence MACE. The cardiorenal syndrome disorder between the heart kidney, where primary dysfunction one organ results secondary damage to other. There are multiple mechanisms involved its pathogenesis, related hemodynamic changes that lead venous congestion, greater volume overload, impaired renal function. Echocardiographic parameters congestion have been AKI MI. Our objective was assess hydration estimated by bioimpedance analysis (BIA) as marker association AKI. Methods Observational study admitted CCU for MI treated PCI. Body composition assessed tetrapolar obtained at 50 kHz. defined 1.5-fold increase serum creatinine from baseline level within 24–48 hours. Mayor adverse cardiovascular events (MACE) during hospitalization were type IV infarction, failure, stroke, or death. Results A total 94 included. median age 58 years (IQR 53 – 63), 89% male. 53% had STEMI, 32% hypertension, 23% diabetes, on admission 0.9 mg/dl 0.75 1.05). occurred 9 (9.7%). Patients MACE (66.7% versus 29.8%, p = 0.02). Total body water (TBW) who suffered AKI, compared those did not (76.8% 75.5%, 0.0008). no significant difference TBW developed failure (75.3% 75.8%, 0.39). Conclusion Among undergoing PCI, status BIA, noninvasive parameter estimate risk developing